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Recombinant human PlGF-1/PGF protein
Recombinant human PlGF-1/PGF protein
- 中文名称:
- Recombinant human PlGF-1/PGF protein
- 英文名称:
- Recombinant human PlGF-1/PGF protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48993
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|0.25 mg
- 保存建议:
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 90% by SDS-PAGE
- 产品形式:
- Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Placenta growth factor (PlGF/PGF) is a member of the PDGF/VEGF-sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. There are three isoforms of this protein: PlGF-1, PlGF-2, PlGF-3. PlGF-2 is only found in early placenta up until the 8th week of development, while PlGF-1 is specifically found in the colon as well as mammary carcinomas. PlGF induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. Also, PlGF is ultimately associated with angiogenesis. These activities facilitate wound, bone fracture, and cardiac repair, but also contribute to inflammation in active sickle cell disease and atherosclerosis. Recombinant human PlGF-1/PGF, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.