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Recombinant human Fc gamma RIIB/CD32b protein
Recombinant human Fc gamma RIIB/CD32b protein
- 中文名称：
- Recombinant human Fc gamma RIIB/CD32b protein
- 英文名称：
- Recombinant human Fc gamma RIIB/CD32b protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA49000
- 规格：
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Fc gamma RIIB/CD32b, also known as FCGR2B, belongs to the Ig superfamily. It is a low-affinity receptor for the Fc region of immunoglobulins gamma that are complexed or aggregated. It participates in various effector and regulatory functions, such as phagocytosis of immune complexes and modulation of antibody production by B cells. Fc gamma RIIB/CD32b is expressed on B cells, monocytes, dendritic cells, neutrophils, mast cells, and basophils. When Fc gamma RIIB is ligated, it inhibits B cell expansion, plasma cell differentiation, production of autoimmune rheumatoid factors, and down-regulates TLR4 with reduced LPS responsiveness. Recombinant human Fc gamma RIIB/CD32b, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
