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Recombinant Human Insulin-like growth factor 1 receptor (IGF1R) Protein
Recombinant Human Insulin-like growth factor 1 receptor (IGF1R) Protein
- 中文名称:
- Recombinant Human Insulin-like growth factor 1 receptor (IGF1R) Protein
- 英文名称:
- Recombinant Human Insulin-like growth factor 1 receptor (IGF1R) Protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA55953
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Store it under sterile conditions at -20°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. The recombinant protein is stable for up to 6 months from date of receipt at -80°C.
- 货期:
- 6-8周
- 纯度:
- > 90 % as determined by SDS-PAGE.
- 产品形式:
- 10 mM Tris-HCl, 1 mM EDTA, pH 8.0, with 50% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
The Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Mice lacking the IGF-1 receptor die late in development, and show a dramatic reduction in body mass, testifying to the strong growth promoting effect of this receptor. Mice carrying only one functional copy of igf1r are normal, but exhibit a ~15% decrease in body mass.