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Recombinant Human MFG-E8 Protein
Recombinant Human MFG-E8 Protein
- 中文名称：
- Recombinant Human MFG-E8 Protein
- 英文名称：
- Recombinant Human MFG-E8 Protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA55954
- 规格：
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store it under sterile conditions at -20°C to -80°C upon receiving.
Stability: The recommended protein is stable for up to 6-12 months from date of receipt at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage.
**Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- > 90 % as determined by SDS-PAGE.
- 产品形式：
- 100 mM Tris-HCI, 0.4 M Arg, pH 8.0, with 50% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
MFGE8 is a protein which is encoded by the MFGE8 gene. MFGE8 is secreted protein found in vertebrates, including mammals as well as birds.Mfge8 contains a phosphatidylserine (PS) binding domain, as well as an Arginine-GlycineAspartic acid motif, which enables the binding to integrins. MFGE8 binds PS, which is exposed on the surface of apoptotic cells. Opsonization of the apoptotic cells and binding to integrins on the surface of phagocytic cells, mediates the engulfment of the dead cell. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. The NIH 3T3 cell transformants that expressed a high level of alpha-V-beta-3 integrin engulfed apoptotic cells when MFGE8 was added.
