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Recombinant SIRT1 (193-741) protein
Recombinant SIRT1 (193-741) protein
- 中文名称：
- Recombinant SIRT1 (193-741) protein
- 英文名称：
- Recombinant SIRT1 (193-741) protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59738
- 规格：
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期：
- 6-8周
- 纯度：
- Recombinant SIRT1 (193-741) protein that includes amino acids 193-741 of human SIRT1 protein (accession number NM_012238.4) was expressed in E Coli and contains an N-terminal GST-Tag with a molecular weight of 101.5 kDa.The purity ofThe protein is > 80% b
- 产品形式：
- Recombinant SIRT1 (193-741) protein is supplied in 25mM Tris pH8.0, 150mM NaCl, 10% glycerol, and 0.5mM TCEP.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Short Description: Recombinant SIRT1 (193-741) protein includes amino acids 193-741 of human SIRT1 protein (accession number NM_012238.4); it was expressed in E Coli and contains an N-terminal GST-Tag with a molecular weight of 101.5 kDa. The purity of the protein is > 60% by SDS-PAGE. It is useful for histone deacetylase assays and the study of DNA Repair.
Background: SIRT1 (Sirtuin 1, SIR2L1) is a member of the Sirtuin family of proteins related to the yeast Sir2 protein. Like Sir2 and other Sirtuins, SIRT1 is an NAD+-dependent histone and protein deacetylase. SIRT1 catalyzes the removal of acetyl groups from a variety of protein substrates (NBS1, p53, Ku70, etc.) as well as from Histone H4 Lys16 (H4K16). SIRT1 is involved in the regulation of a number of cellular processes, including transcription, metabolism, DNA repair and aging, and increased SIRT1 is associated with extended lifespan of C. elegans.
