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Recombinant SIRT3 (102-399) protein
Recombinant SIRT3 (102-399) protein
- 中文名称:
- Recombinant SIRT3 (102-399) protein
- 英文名称:
- Recombinant SIRT3 (102-399) protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59737
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 纯度:
- Recombinant SIRT3 (102-399) protein that includes amino acids 102-399 of human SIRT3 protein (accession number NM_012239.5) was expressed in E Coli and contains an N-terminal GST-Tag with a molecular weight of 59.7 kDa.The purity ofThe protein is > 60% by
- 产品形式:
- Recombinant SIRT3 (102-399) protein is supplied in 25mM Tris pH8.0, 150mM NaCl, 5% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Short Description: Recombinant SIRT3 (102-399) protein includes amino acids 102-399 of human SIRT3 protein (accession number NM_012239.5); it was expressed in E Coli and contains an N-terminal GST-Tag with a molecular weight of 59.7 kDa. The purity of the protein is > 60% by SDS-PAGE. It is suitable for histone and other protein deacetylase assays and use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: SIRT3 (Sirtuin 3) is a member of the SIR2/Sirtuin family of NAD+-dependant deacetylase enzymes. Sirtuin family enzymes can be found in the cytoplasm, mitochondria or nucleus of a cell and are ubiquitously expressed. SIRT3 has multiple targets for deacetylation, including ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. SIRT3 contributes to the regulation of the cellular energy metabolism and tissue-specifc ATP levels.