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Human Interferon alpha-2b (INF alpha-2b), yeast
Human Interferon alpha-2b (INF alpha-2b), yeast
- 中文名称：
- Human Interferon alpha-2b (INF alpha-2b), yeast
- 英文名称：
- Human Interferon alpha-2b (INF alpha-2b), yeast
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA62203
- 规格：
- 0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg|5x0.02 mg
- 保存建议：
- Stable for 6-months from the date of shipment when kept at -20 degree C or -70 degree C. Upon reconstitution, it can be stored at 4 degree C for at least one month or -20 degree C for at least three months. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- > 97% (by SDS-PAGE and HPLC)
- 产品形式：
- Lyophilized from a 0.2mum filtered solution in 20mM Phosphate Buffer
Reconstitute with double distilled water at a concentration of no less than 1 mug/ml with 0.1% human serum albumin (A highly purified plant-derived human serum albumin is strongly sug
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant human IFN alpha-2b produced in Yeast is a single, non-glycosylated, polypeptide chain containing 165 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 19.3kD.
Introduction: Human Interferon alpha-2b is a single polypeptide chain of 165 amino acids residues, containing 4 Cys to form two disulfide bonds at positions of Cys 1- Cys 98 and Cys 29-Cys 138, and it has a molecular mass of approximately 19.3 kD. IFN can exert certain cell activities through binding to specific cell surface receptors, as firstly induce to develop special proteins, such as protein kinase and 2', 5'-oligo polyadenylic acid synthase etc. The unique character of two enzymes is that they can be activated respectively by double chains RNA to produce the effect of self-phosphorylation. INF can also enhance phagocytosis activity of macrophage and special toxicity of lymphocyte to target cells to cause immunoloregulation. Its biological effects contains: (1) Anti-virus: INF alpha has broad-spectrum anti-virus effect; (2) Cytostatic effect to certain cells; (3) Immunoloregulation effect: accelerate the expression of MHC antigen by most cell and active NK cell and CTL. (4) Repress and kill tumor cells: INF-alpha kill the tumor cells through accelerating the immunological function and enhancing the killing ability of macrophage, NK and CTL.
