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PAD6 recombinant protein
PAD6 recombinant protein
- 中文名称:
- PAD6 recombinant protein
- 英文名称:
- PAD6 recombinant protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA72908
- 规格:
- 0.02 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Stability: 1 year at -70°C from date of shipment.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant protein stored in 50mM Tris-HCI, pH 7.5, 50mM NaCI, 10 mM glutathione,0.1 mM EDTA, 0.25mM DTT, 0.01 PMSF, 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Recombinant full-length human PAD6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_207421.
Scientific Background PAD6 or PADI6 is a member of the peptidylarginine deiminases which convert arginine residues to citru lline residues in the presence of calcium ions. The PAD family members are thought to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis 1). PAD6 is essent ial for formation of a novel oocyte-restricted fibrous structure, the cytoplasmic lattices CPLs). PAD6/CPL superstru cture plays a key role in regulating microtubule-mediated organelle positioning and movement (2).