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2019-nCoV RdRp, Active
2019-nCoV RdRp, Active
- 中文名称:
- 2019-nCoV RdRp, Active
- 英文名称:
- 2019-nCoV RdRp, Active
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA73171
- 规格:
- 0.005 mg|0.01 mg|0.02 mg|0.05 mg|2x0.05 mg
- 保存建议:
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- 50mM sodium phosphate, pH7.5, 300mM NaCl, 150mM imidazole, 1mM DTT, 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Recombinant 2019-nCoV RNA-dependent RNA polymerase (RdRp) was expressed in E Coli cells using a C-terminal His tag.
Overview: A novel Corona virus (SARS-CoV-2) has caused a global COVID-19 pandemic of respiratory disease in 2020 (1). RNA-dependent RNA polymerase (RdRp) is an enzyme that is crucial to life cycle of RNA viruses including Corona viruses (2). RdRp catalyzes the synthesis of viral RNA, thereby playing a central role in the replication and transcription cycle of COVID-19 viruses, possibly in complex with nsp7 and nsp8 (3). Therefore, RdRp is a prime target for nucleotide analog antiviral inhibitors, such as remedesivir, for development of new antiviral therapeutics (4).