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CD147 (22-205) Protein
CD147 (22-205) Protein
- 中文名称：
- CD147 (22-205) Protein
- 英文名称：
- CD147 (22-205) Protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73175
- 规格：
- 0.005 mg|0.01 mg|0.02 mg|0.05 mg|2x0.05 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- 50mM Tris-HCl, pH7.5, 90mM glycine
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human CD147 (22-205) protein was expressed in CHO cells using a C-terminal Fc tag. The gene accession number is NM_198589
Overview: CD147 is a highly glycosylated transmembrane protein that acts as the main upstream stimulator of matrix metalloproteinases (MMPs) (1). It has been reported to bind viral Spike protein of SARS-Co-2, thereby playing a functional role in mediating the viral invasion of the host cell. CD147 also acts as an RBC receptor for Plasmodium falciparum, a Malarial protozoan (2). In addition, expression level of CD147 is increased in tumor tissue, inflammation and pathogenically infected cells. Therefore, CD147 receptor blocking drugs may provide novel therapeutic strategy against viral invasion, such as 2019-nCoV (3).
