-
BAP1, Active
BAP1, Active
- 中文名称：
- BAP1, Active
- 英文名称：
- BAP1, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73284
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM sodium phosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant full-length human BAP1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. The BAP1 gene accession number is NM_004656.
BAP1 (BRCA1 associated protein-1) is a deubiquitinating enzyme belonging to the ubiquitin C-terminal hydrolase subfamily and is involved in the ubiquitin removal from proteins. It binds to the RING finger domain of the BCRA1 and acts as a tumor suppressor (1). BAP1 mutations have been found to cause multiple tumour types and high tumour phenotype penetrance, suggesting that it may have a major role in inducing cancer growth (2).
