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TNFAIP3 (A20p37), Active
TNFAIP3 (A20p37), Active
- 中文名称:
- TNFAIP3 (A20p37), Active
- 英文名称:
- TNFAIP3 (A20p37), Active
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA74075
- 规格:
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议:
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant protein stored in 50mM sodium phosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Recombinant human TNFAIP3 (440-790 a.a.), or A20p37, was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. The TNFAIP3 gene accession number is NM_006290.
TNFAIP3 (Tumor necrosis factor alpha-induced protein 3) is a ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. The enzyme plays a role in immune and inflammatory responses of cytokines such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through inhibiting NFkB activity (1). TNFAIP3 has been found to be associated with rheumatoid arthritis (2).