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USP11, Active
USP11, Active
- 中文名称：
- USP11, Active
- 英文名称：
- USP11, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA74100
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >90%
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant full-length human USP11 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The USP11 gene accession number is NM_004651.
USP11 (ubiquitin carboxyl-terminal hydrolase 11) is a member of the ubiquitin specific proteases family (USPs) and is a protease that functions in the removal of conjugated ubiquitin from target proteins and polyubiquitin chains. The enzyme cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains and is involved in regulating pathways that lead to NF-kappa-B activation by regulating IkappaB kinase alpha (1). USP11 also binds to p21, a cyclin-dependent kinase inhibitor and plays an important role in regulating cell-cycle progression and DNA damage responses.
