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Flagellin [FliC] (high purity)
Flagellin [FliC] (high purity)
- 中文名称:
- Flagellin [FliC] (high purity)
- 英文名称:
- Flagellin [FliC] (high purity)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77036
- 规格:
- INQUIRE
- 保存建议:
- Stable for at least 6 months after receipt when stored at -20 degree C
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20 degree C
Shipping: Shipped on Blue Ice
- 货期:
- 6-8周
- 纯度:
- >=95% (SDS-PAGE)
- 产品形式:
- Lyophilized. Contains PBS
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Motile bacteria produce flagella, filaments composed mainly of the structural subunit flagellin. Flagellins are highly conserved molecules among both gram negative and gram positive bacteria, especially in 170 N-terminal and 100 C-terminal amino acids. In mammalian cells, Toll-like receptor 5 (TLR5) senses various flagellins resulting in activation of innate and adaptive immunity. The phase 1 flagellin FliC from Salmonella typhimurium (serotype H 'I'), a protein of 494 amino acids, upregulates production of chemokines and antimicrobial compounds in human epithelial cells and monocytes and induces maturation of dendritic cells. Historical results have shown that flagellin tests positive for activation of HEK-Blue hTLR5 reporter cell line (Invivogen) at concentrations >1 pg/ml.