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Tyrosinase (human), (recombinant) (His-tag)
Tyrosinase (human), (recombinant) (His-tag)
- 中文名称：
- Tyrosinase (human), (recombinant) (His-tag)
- 英文名称：
- Tyrosinase (human), (recombinant) (His-tag)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77051
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- For long term storage, store at -80 degree C. Avoid freeze/thaw cycles
Shipping: Shipped on Dry Ice
- 货期：
- 6-8周
- 纯度：
- >=85% (SDS-PAGE)
Purified by multi-step chromatography
- 产品形式：
- Liquid. In 50mM TRIS/HCl, pH8.0, 1M NaCl, 0.05% Empigen BB, and 30% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Tyrosinase is a copper-containing enzyme that catalyzes four steps in the melanin and catecholamine synthesis pathways. Like tyrosine hydroxylase (EC 1.13.16.2), it can catalyze the formation of L-DOPA in the brain and nervous system. It oxidizes monophenols, but like catecholoxidase (EC 1.10.3.1), it can also oxidize o-diphenols to o-quinones. It is involved in cancer, Parkinson's, pigmentation diseases, Alzheimer's and obesity. Much of the research and inhibitor screening has used mushroom tyrosinase. However, mushroom tyrosinase interacts very differently with substrates and inhibitors compared to the human enzyme. In addition, commercially available mushroom tyrosinase is not always of good purity. Recombinant versions of human tyrosinase amino acids 1-345 or 1-378, also available commercially, are not functional due the lack of critical catalytic and structural residues.
