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Human parvovirus VP1
Human parvovirus VP1
- 中文名称:
- Human parvovirus VP1
- 英文名称:
- Human parvovirus VP1
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77993
- 规格:
- 1 mg|2 mg|5 mg|2x5 mg|3x5 mg
- 保存建议:
- Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >90% pure (10% SDS-PAGE, Coomassie stain). Proprietary chromatographic technique
- 产品形式:
- Liquid. PBS / 25mM K2CO3
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Human parvovirus B19 is a causative agent of common childhood infection, erythema infectiosum. B19 is also a major cause of apalstic crises, there is 9% risk for fetal loss in infected pregnancy. It can cause hydro feralis, and has been shown to be the cause of persistant severe anaemia in immunocomprised individuals including children with acute lymphatic leukaemia and patients with HI.
Parvovirus B19 is a small DNA virus with limited genome about 5.4 Kb. This virus arranges its genome with the left side encoding non-structural proteins NS1 and right side encoding structural protein, VP1 and VP2. VP1 and VP2 encodes in the same reading frame with identical sequence except additional 227 amino acids at the amino terminus of VP1 protein. Monoclonal antibody mapmstudy indicated that most antigenicity of VP1 is located at its N-terminus.
Recombinant parvovirus VP1 protein contains 227 amino acids derived from N-terminus of VP1 protein sequence. The recombinant protein was expressed and purified from E Coli, the purified recombinant protein is used to test Parvovirus B19 specific antibody for research or clinical study.