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Recombinant Toxoplasma gondii SAG2 antigen (P22)
Recombinant Toxoplasma gondii SAG2 antigen (P22)
- 中文名称:
- Recombinant Toxoplasma gondii SAG2 antigen (P22)
- 英文名称:
- Recombinant Toxoplasma gondii SAG2 antigen (P22)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77994
- 规格:
- 1 mg|2 mg|5 mg|2x5 mg|3x5 mg
- 保存建议:
- Upon receipt, store at -20°C. Avoid mulitple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >95% pure (12% SDS-PAGE, Coomassie blue stain); Proprietary chromatographic technique
- 产品形式:
- Purified, Liquid; Phosphate buffered saline
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Toxoplasma gondii is an obligate intracellular protozoan parasite, it has been known associating with severe congenital defects and life threatening infection in immunocompromised hosts. In human, T. gondii infection in pregnant women can result in congenital infection, such as late-onset eye disease, it is also a frequent cause of encephalitis in AIDS patients; in animal, the infection can cause a variety diseases and symptoms. Surface antigen 2 (SAG2 or P22) of T. gondii is a major surface protein with the function as attachment ligand. It shows with good antigenicity and immunogenicity. rSAG2 expressed in E. coli contains full length amino acid sequence and 6 x his tag at its C-terminus. rSAG2 was effective to detect IgG to T. gondii in human patients with acute toxoplasmosis. It is used as an antigen in ELISA to test T. gondii infection in domestic cats as well. It has been proved that rSAG2 could provide partial protection against a lethal infection of T. gondii and inhibited cyst formation in the brains of infected mice.