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CD274 (B7-H1)-muIg-Biotin
CD274 (B7-H1)-muIg-Biotin
- 中文名称：
- CD274 (B7-H1)-muIg-Biotin
- 英文名称：
- CD274 (B7-H1)-muIg-Biotin
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78192
- 规格：
- 0.025 mg|2x0.025 mg|3x0.025 mg|4x0.025 mg|5x0.025 mg
- 保存建议：
- Store at 2 - 5 degree C. Freeze/Thawing is not recommended
Product should retain activity for at least 6 months after shipping date when stored as recommended.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Information: CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation, and is involved in progression of cancer, arthritis and HIV infection (3). CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in Renal cell carcinoma are associated with poor prognosis (1). Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival (2). Gamma Interferon and PHA can up regulate CD274 expression on T cells.
