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CD152(CTLA-4)-muIg-Biotin
CD152(CTLA-4)-muIg-Biotin
- 中文名称：
- CD152(CTLA-4)-muIg-Biotin
- 英文名称：
- CD152(CTLA-4)-muIg-Biotin
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78196
- 规格：
- 0.025 mg|2x0.025 mg|3x0.025 mg|4x0.025 mg|5x0.025 mg
- 保存建议：
- Store at 2 - 5 degree C. Freeze/Thawing is not recommended.
Product should retain activity for at least 12 months after shipping date when stored as recommended.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Information: Immune response mediated by T cells can be characterized to functionally proceed as follows: antigen recognition by the T cell receptor, activation through costimulation, effector activities to eliminate antigen and finally down regulation. Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses. The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 (B7-1) and CD86 (B7-2). CD152 Ig will block the binding of anti-CD80 (B7-1) and anti-CD86 (B7-2) monoclonal antibodies.
