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Recombinant human CCR8 protein with C-terminal human Fc tag
Recombinant human CCR8 protein with C-terminal human Fc tag
- 中文名称：
- Recombinant human CCR8 protein with C-terminal human Fc tag
- 英文名称：
- Recombinant human CCR8 protein with C-terminal human Fc tag
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78605
- 规格：
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议：
- Store protein at -20 degree C. Aliquot the product to avoid repeated freezing/thawing cycles. Protein can be stored at 4 degree C for a limited period of time.
- 货期：
- 6-8周
- 纯度：
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- 产品形式：
- Lyophilized from sterile PBS, pH7.4. Normally 5 %-8% trehalose is added as protectants before lyophilization.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
The protein has a predicted molecular mass of 29.37 kDa after removal of the signal peptide. CCR8 (Met 1-Lys 35), hFc (Glu 99-Ala330). This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
