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Human CD14, soluble
Human CD14, soluble
- 中文名称:
- Human CD14, soluble
- 英文名称:
- Human CD14, soluble
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA79182
- 规格:
- 0.01 mg|0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg
- 保存建议:
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C.
Stability: Lyophilized CD14 should be stored desiccated below -20 degree C. Upon reconstitution CDNF should be stored at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE gel and HPLC analysis.
- 产品形式:
- Lyophilized from 10mM Sodium Phosphate, pH 7.5
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
CD14 is a cell surface anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor.