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Human MIA (Melanoma inhibitory activity)
Human MIA (Melanoma inhibitory activity)
- 中文名称：
- Human MIA (Melanoma inhibitory activity)
- 英文名称：
- Human MIA (Melanoma inhibitory activity)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79186
- 规格：
- 0.005 mg|0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg
- 保存建议：
- The lyophilized protein is stable at 4°C. Reconstituted working aliquots are stable at 2°C to 8°C.
- 货期：
- 6-8周
- 纯度：
- > 98% by SDS-PAGE and HPLC analysis
- 产品形式：
- Lyophilized; 15mM Sodium Phosphate, pH 7.2 + 75mM NaC1
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for identification of melanoma metastasis as well as a potential marker for rheumatoid arthritis. Recombinant human MIA is a 12.2 kDa globular protein containing 108 amino acid residues including two intramolecular disulfide bonds..
