
-
Human GDF-11
Human GDF-11
- 中文名称:
- Human GDF-11
- 英文名称:
- Human GDF-11
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA79190
- 规格:
- 0.005 mg|0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg
- 保存建议:
- The lyophilized protein is stable at room temperature for up to 1 month at 4 degree for 6 months. Working aliquots stored with a carrier protein are stable for at least 6 months at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- > 98% by SDS-PAGE and HPLC analysis
- 产品形式:
- Lyophilized
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.