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Recombinant Mouse FGF-23
Recombinant Mouse FGF-23
- 中文名称:
- Recombinant Mouse FGF-23
- 英文名称:
- Recombinant Mouse FGF-23
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA79235
- 规格:
- 0.005 mg|0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg
- 保存建议:
- The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE & HPLC analyses
- 产品形式:
- Lyophilized
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
The FGF family plays a central role during prenatal development and postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.