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Human Neurturin
Human Neurturin
- 中文名称：
- Human Neurturin
- 英文名称：
- Human Neurturin
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79278
- 规格：
- 0.005 mg|0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg
- 保存建议：
- Store at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C
- 货期：
- 6-8周
- 纯度：
- > 98% by SDS-PAGE and HPLC analysis
- 产品形式：
- Lyophilized from 10 mM Sodium Citrate, pH 4.0
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRalpha2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (204 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.
