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Human DLL-4, soluble
Human DLL-4, soluble
- 中文名称：
- Human DLL-4, soluble
- 英文名称：
- Human DLL-4, soluble
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79284
- 规格：
- 0.005 mg|0.025 mg|2x0.025 mg|3x0.025 mg|4x0.025 mg
- 保存建议：
- Reconstituted working aliquots are stable for 1 week at 2°C to 8°C. For 3 months at -20°C to -80°C.
- 货期：
- 6-8周
- 纯度：
- > 95%, by SDS-PAGE and HPLC analysis
- 产品形式：
- Lyophilized form 1X PBS, pH 7.5
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Human sDLL4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. DLL4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL4 gene in mice resulted in severe vascular defects and death before birth. Up-regulation of DLL4 expression has been implicated in the vascular development of certain tumors. Recombinant human sDLL4 is a 54.0 kDa glycoprotein containing 498 amino-acid residues.
