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Human Semaphorin 3A
Human Semaphorin 3A
- 中文名称：
- Human Semaphorin 3A
- 英文名称：
- Human Semaphorin 3A
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79294
- 规格：
- 0.005 mg|0.025 mg|2x0.025 mg|3x0.025 mg|4x0.025 mg
- 保存建议：
- The lyophilized prctein is stable at room temperature for 1 month and at 4°C for 3 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE & HPLC analyses
- 产品形式：
- Lyophilized from 20mM Tris, pH 8.0 Lyophlized ( 10mM Tris, pH 8.8 + 100mM NaCI)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500 amino acid SEMA domain at the amino terminus. Classes 3,4,6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Semaphorin 3A is a 751 amino acid protein containing the SEMA domain, an immunoglobulin c2-like domain and a basic domain (Arg/Lys rich) near the C-terminus.
