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Anti-GFAP-R416WT Antibody
Anti-GFAP-R416WT Antibody
- 中文名称：
- Anti-GFAP-R416WT Antibody
- 英文名称：
- Anti-GFAP-R416WT Antibody
- 品牌：
- NeuroMab
- 品牌介绍：
- NeuroMab是美国国立卫生研究院神经单抗研究所成立于2004年，旨在生产可用于神经学研究的小鼠单克隆抗体。这些抗体广泛应用于动物脑组织样本检测，包括免疫印迹、免疫组化等。引用NeuroMab的产品发表的文献，已超过：3300篇。
- 货号：
- 75-279
- 规格：
- 100 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers .
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Mouse, and Rat
- 应用：
- WB, IHC, ICC, ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Our Anti-GFAP-R416WT mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N206B/9. It is KO validated, detects human, mouse, and rat GFAP-R416WT, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
