-
Anti-Glycine Receptor Alpha3L Antibody FL490 Conjugate
Anti-Glycine Receptor Alpha3L Antibody FL490 Conjugate
- 中文名称：
- Anti-Glycine Receptor Alpha3L Antibody FL490 Conjugate
- 英文名称：
- Anti-Glycine Receptor Alpha3L Antibody FL490 Conjugate
- 品牌：
- NeuroMab
- 品牌介绍：
- NeuroMab是美国国立卫生研究院神经单抗研究所成立于2004年，旨在生产可用于神经学研究的小鼠单克隆抗体。这些抗体广泛应用于动物脑组织样本检测，包括免疫印迹、免疫组化等。引用NeuroMab的产品发表的文献，已超过：3300篇。
- 货号：
- 75-427-FL490
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission (Schofield et al., 2003). The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane hyperpolarization. Glycine receptors are anchored at inhibitory chemical synapses by a cytoplasmic protein, gephyrin (Fischer et al., 2000). The glycine receptor has been used to great advantage in the identification of the binding sites for alcohol on the LGIC family of proteins (Beckstead et al., 2001; Mihic et al., 1997). These receptors have also been extremely useful in studies of synaptic clustering of receptors (Craig and Lichtman, 2001). The glycine receptor may also act in concert with an NMDAR subunit to form an excitatory receptor (Chatterton et al., 2002).
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- IHC, ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
- 说明书：
Our Anti-Glycine receptor Alpha3L mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N424/48. It detects human Glycine receptor Alpha3L, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
