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Anti-GOLGA2 (GM130) Antibody
Anti-GOLGA2 (GM130) Antibody
- 中文名称：
- Anti-GOLGA2 (GM130) Antibody
- 英文名称：
- Anti-GOLGA2 (GM130) Antibody
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- GOLGA2-0020
- 规格：
- 100 µL
- 保存建议：
- Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
- 背景资料：
- GOLGA2, also known as GM130, is a Golgi matrix protein critical for the proper functioning and organization of the Golgi apparatus. Discovered in the mid-1990s, GOLGA2 is involved in the maintenance of Golgi structure and the facilitation of vesicle trafficking within the cell. This protein is pivotal in ensuring that proteins and lipids are correctly modified, sorted, and sent to their destined locations, which is essential for various cellular processes including secretion, plasma membrane repair, and lysosome function. GOLGA2's role in cellular homeostasis and its effect on the Golgi apparatus associates it with several neurodegenerative and congenital disorders. Mutations in the gene and dysfunction of the protein can lead to brain development delays, and diseases such as Parkinson’s and ALS (Huang et al. 2021). Also, changes in GOLGA2 levels can affect Golgi structure and vesicle trafficking leading to aberrant cell proliferation, tumorigenesis and metastasis, making GOLGA2 a target of anti-cancer gene therapy (Chang et al. 2012).
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Human
- 应用：
- ICC, IHC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:200 µg/mL
推荐稀释比（WB）:1:500-1:2000
推荐稀释比（IHC）:1:100-1:500
推荐稀释比（ICC）:1:100-1:500
- 说明书：
Our Anti-GOLGA2 (GM130) chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human GOLGA2 (GM130) , and is affinity-purified IgY. It is great for use in IHC, ICC, WB.
