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Anti-GOLGB1 (Giantin) Antibody
Anti-GOLGB1 (Giantin) Antibody
- 中文名称：
- Anti-GOLGB1 (Giantin) Antibody
- 英文名称：
- Anti-GOLGB1 (Giantin) Antibody
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- GOLGB1-0100
- 规格：
- 500 µL
- 保存建议：
- Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
- 背景资料：
- GOLGB1, also known as Giantin, is a protein associated with the Golgi apparatus, playing a key role in maintaining its structural integrity and facilitating vesicle trafficking between the endoplasmic reticulum and the Golgi. Discovered within the context of Golgi apparatus research initiated by Camillo Golgi in 1898, the molecular cloning and sequencing of the GOLGB1 gene in the early 1990s allowed detailed studies of its structure and function, revealing its role in stacking Golgi cisternae and influencing various cell signaling pathways. Functional studies, including knockdown and knockout experiments (Satoh et al 2019), have demonstrated GOLGB1’s importance in maintaining Golgi integrity. A myriad of diseases are associated with Golgi dysfunction, including neurodegenerative diseases such as ALS, Alzheimer’s, and Parkinson’s, as well as cancer and congenital disorders of glycosylation (Lan etc al, 2016). In time, GOLGB1 (Giantin) could potentially serve as a therapeutic target for many of these conditions.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Human
- 应用：
- ICC, IHC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:200 µg/mL
推荐稀释比（IHC）:1:100-1:500
推荐稀释比（ICC）:1:100-1:500
- 说明书：
Our Anti-GOLGB1 (Giantin) chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human GOLGB1 (Giantin), and is affinity-purified IgY. It is great for use in IHC and ICC.
