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Camptothecin
Camptothecin
- 中文名称：
- Camptothecin
- 英文名称：
- Camptothecin
- 品牌：
- Immuno Chemistry
- 货号：
- 6208
- 规格：
- 25 mg
- 保存建议：
- -20°C
- 背景资料：
- Camptothecin is a potent cytotoxic pentacyclic alkaloid known for its potent apoptosis inducing properties. Camptothecin and its analogs have been demonstrated to inhibit topoisomerase I (topo I), causing cells in S phase to enter into apoptosis. Camptothecin binds to and stabilizes the topo I – DNA backbone complex (covalent binary complex). This stabilized complex diminishes the rate of topo I release from the broken strand, thus slowing the religation and subsequent DNA synthesis process. Use camptothecin to create positive controls in apoptosis detection experiments.
- 货期：
- 4-6周
- 样本类型：
- Cell culture
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Camptothecin, a cytotoxic plant alkaloid with antitumor properties, is a prototypic DNA topoisomerase I inhibitor. Use camptothecin to create positive controls in apoptosis detection experiments.
