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Anti-Tyrosine Kinase Receptor B (TrkB) Antibody
Anti-Tyrosine Kinase Receptor B (TrkB) Antibody
- 中文名称：
- Anti-Tyrosine Kinase Receptor B (TrkB) Antibody
- 英文名称：
- Anti-Tyrosine Kinase Receptor B (TrkB) Antibody
- 品牌：
- Biosensis
- 货号：
- R-149-100
- 规格：
- 100 µL
- 保存建议：
- Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- 背景资料：
- TrkB is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). It is Involved in the development and/or maintenance of the nervous system. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. ALTERNATIVE PRODUCTS: 4 named isoforms produced by alternative splicing. Additional isoforms seem to exist. TISSUE SPECIFICITY: The different forms are differentially expressed in various cell types. SIMILARITY: Belongs to the Tyr protein kinase family. Insulin receptor subfamily. SIMILARITY: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. SIMILARITY: Contains 2 LRR (leucine-rich) repeats. SIMILARITY: Contains 1 protein kinase domain. Mutations in the TrkB gene have been associated with obesity and mood disorders.
- 货期：
- 4-6周
- 来源宿主：
- Rabbit
- 应用：
- ELISA, IHC-Frozen
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Tyrosine Kinase Receptor B (TrkB) rabbit polyclonal primary antibody detects mouse and rat Tyrosine Kinase Receptor B (TrkB), and is whole serum. It is validated for use in ELISA, IHC-Frozen.
