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Recombinant Neutrophil Elastase/ELA2
Recombinant Neutrophil Elastase/ELA2
- 中文名称：
- Recombinant Neutrophil Elastase/ELA2
- 英文名称：
- Recombinant Neutrophil Elastase/ELA2
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48315
- 规格：
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议：
- For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- CAS号：
- 483-15-8
- 纯度：
- >90% by SDS-PAGE
- 属性（合成/天然）：
- 天然
- 产品形式：
- Liquid; In 20mM Tris-HCl Buffer (pH 8.0) Containing 0.1M NaCl, 30% Glycerol.
- 分子量：
- 337.37 g/mol
- 分子式：
- C20H19NO4
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Neutrophil Elastase, also known as polymorphonuclear leukocyte eslastase, is a serine protease that classified as the chymotrypsin family. This protein breaks down elastin, an elastic fiber together with collagen and determines the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A (OmpA) of E Coli and other Gram-negative bacteria. Also, this protein is inhibited by the acute-phase protein alpha1-antitrypsin (A1AT), which binds almost irreversibly to the active site of elastase and trypsin. A1AT is normally secreted by the liver cells into the serum. Alpha-1-antitrypsin deficiency (A1AD) leads to uninhibited destruction of elastic fiber by elastase. Recombinant Mouse Neutrophil Elastase, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
