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MGMT, 1-207aa, Human, His tag, E Coli
MGMT, 1-207aa, Human, His tag, E Coli
- 中文名称：
- MGMT, 1-207aa, Human, His tag, E Coli
- 英文名称：
- MGMT, 1-207aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48518
- 规格：
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- CAS号：
- 485-18-7
- 纯度：
- > 95% by SDS-PAGE
- 属性（合成/天然）：
- 天然
- 产品形式：
- Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 10% glycerol
- 分子量：
- 596.7 g/mol
- 分子式：
- C36H40N2O6
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
O-6-methylguanine-DNA methyltransferase (MGMT) is an enzyme that repairs O-6-methylguanine, a mutagenic DNA base damaged by endogenous and environmental alkylating agents and is involved in the cellular defense against the biological effects of O-6-methylguanine in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. There are few reports that abnormal MGMT expression correlates with the prognosis in human solid cancers. Recombinant MGMT, fused to His-tag at N-terminus, was expressed in E Coli and was purified by conventional chromatography techniques.
