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TCL1A, 1-114aa, Human, E Coli
TCL1A, 1-114aa, Human, E Coli
- 中文名称：
- TCL1A, 1-114aa, Human, E Coli
- 英文名称：
- TCL1A, 1-114aa, Human, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48561
- 规格：
- 0.02 mg|0.1 mg|0.5 mg|5x0.02 mg|5x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- CAS号：
- 485-61-0
- 纯度：
- > 90% by SDS-PAGE
- 属性（合成/天然）：
- 天然
- 产品形式：
- Liquid. In 50mM Tris-HCl Buffer (pH 7.5) containing 10% glycerol
- 分子量：
- 279.29 g/mol
- 分子式：
- C17H13NO3
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E Coli and purified by using conventional chromatography techniques
