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ADCY5 Antibody
ADCY5 Antibody
- 中文名称：
- ADCY5 Antibody
- 英文名称：
- ADCY5 Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA75708
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Store at -20°C for long term storage.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Rat, Mouse
- 应用：
- WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, DB (Dot Blot), CM (Confocal Microscopy)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:N/A
同型:N/A
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Affinity Purified Immunoglobulins
浓度：N/A
- 说明书：
The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G prolein-coupled receptors. Nine human AC isoforms (AC-1 through AC-9), encoded by separate genes, have been identified up to now (1). Most of the adenylate cyclase genes are comprise of 11-26 exons and distributed over a q6-430 kb. Majority of the adenylate cyclases previously described are expressed discretely in defined peripheral tissues, the type 4 adenylate cyclase (AC4) is apparenlly expressed in a variety of peripheral tissues and in the central nervous system, mainly in olfactory system. AC-5 is localized on photoreceptor cells and are also designated as GCl and GC2. The AC-S protein resembles the other adenylyl cyclases in its predicted and proposed structure. AC-5 resembles the type 6 (AC-6) adenylyl cyclase in its amino acid sequence but becomes divergent at N and C-terminal ends. The AC5 and AC6 proteins are colocalized in most of the visual organs (photoreceptor cells) are associated with other protein complexes. Both AC5 and AC6 enzymes play an important role in synaptic plasticity by coordinating overlapping synaptic inputs from Gs and Gi coupled receptor stimulation (3).
The Anti-AC5-seleclive antibodies were generated against conserved sequences alar near the C-Ierminal end of the protein that are unique to AC5-protein. The AC5-selective antibodies are affinity purified against immobilized antigen based affinity chromatography which yielded epitope-specific antibodies. The AC4 antibodies label a 127-130 kDa protein in Westem blot positive control and in rat ol factory bUlb. Anti-AC5-selective antibodies are also available in affinity-purified form for confocal, WB and IHC analyses.
