-
PDYN/ProDynorphin Antibody, Rabbit PAb, Antigen Affinity Purified
PDYN/ProDynorphin Antibody, Rabbit PAb, Antigen Affinity Purified
- 中文名称：
- PDYN/ProDynorphin Antibody, Rabbit PAb, Antigen Affinity Purified
- 英文名称：
- PDYN/ProDynorphin Antibody, Rabbit PAb, Antigen Affinity Purified
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258657
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:Human PDYN/ProDynorphin
纯度:N/A
形式：N/A
浓度：N/A
- 说明书：
Dynorphin peptides, derived from the prodynorphin (PDYN) precursor, bind to opioid receptors, preferentially the kappa-opioid receptor (KOR), and may mediate the aversive effects of drugs of abuse. Dynorphin peptides produce place aversion in animals and produce dysphoria in humans. DYNs mediate alcohol-induced impairment of learning and memory, while KOR antagonists block excessive, compulsive-like drug and alcohol self-administration in animal models. Cocaine and heroin have both been shown to increase the expression of PDYN in brain regions relevant for drug reward and use. Polymorphisms in PDYN are therefore hypothesized to increase the risk for addiction to drugs of abuse. Within the core promoter region of PDYN, a 68-bp sequence was found to occur as a polymorphism element, either singular or as tandemly repeated two, three, or four times.
