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Anti Valerylfentanyl Carboxylic acid mouse monoclonal antibody
Anti Valerylfentanyl Carboxylic acid mouse monoclonal antibody
- 中文名称：
- Anti Valerylfentanyl Carboxylic acid mouse monoclonal antibody
- 英文名称：
- Anti Valerylfentanyl Carboxylic acid mouse monoclonal antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA41072
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|5x0.1 mg|4x0.1 mg
- 保存建议：
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4°C for frequent use.
Store at -20 to -80°C for 12 months from the date of receipt
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- CAS # 117332-91-9
- 应用：
- ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[95-F-6]
特异性:N/A
纯度:Protein G purified from mice ascites
形式：Liquid
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度：1.53 mg/ml
- 说明书：
Valerylfentanyl first appeared in toxicological assays in 2016 and through 2018, it has been reported in 6 countries worldwide, including North America, Europe, and Asia. It is being sold as heroin, an adulterant in heroin, or as counterfeit pills. Few fatalities have been attributed to this substance although confiscations of drug containing valerylfentanyl appear to be increasing in some states in the U.S. Receptor binding data show that valerylfentanyl binds selectively to the mu subtype of opioid receptors with low nanomolar affinity relative to kappa and delta opioid receptors. Functional binding assays suggest that valerylfentanyl is a partial agonist at mu and kappa opioid receptors and an antagonist at delta receptors. However, in vivo pharmacology studies in rodents and non-human primates suggest that valerylfentanyl is a full mu agonist.No pharmacokinetic studies of valerylfentanyl are reported in the preclinical or clinical scientific literature. Valerylfentanyl appears to be less potent than other illicit mu agonists with a chemical structure that is similar to fentanyl. As such, its pharmacology and toxic effects are likely to be similar to fentanyl. It currently has no legitimate medical or veterinary uses and is relatively easy to manufacture. The totality of data currently available on valerylfentanyl suggests that it has high abuse potential and poses a serious public health threat.
