
-
Anti D-Dimer mouse monoclonal antibody
Anti D-Dimer mouse monoclonal antibody
- 中文名称:
- Anti D-Dimer mouse monoclonal antibody
- 英文名称:
- Anti D-Dimer mouse monoclonal antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA41073
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|5x0.1 mg|4x0.1 mg
- 保存建议:
- Store at -20 to -80 °C for twelve months from the date of receipt.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Homo sapiens (Human)
- 应用:
- IHC (Immunohistochemistry), WB (Western Blot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1
克隆号:[50-A-9]
特异性:N/A
纯度:N/A
形式:Liquid. Supplied as solution form in PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度:0.87 mg/ml
- 说明书:
Background: The liver produces several important proteins involved in the coagulation process, one of which includes fibrinogen. A single fibrinogen molecule is a symmetrical dimer that is made up of three pairs of three different polypeptide chains, which include a, b and g. Each of the intertwined polypeptide chains that comprise a single fibrinogen molecule is held together by disulfide bonds. The formation of fibrin begins with the cleaving of the a and b polypeptide chains of the fibrinogen molecule, which is achieved by thrombin. This cleaving event causes the fibrin monomers to spontaneously polymerize, which results in the formation of double-stranded fibrin protofibrils.To strengthen a normally weak network that exists between the fibrin monomers and the protofibrils, a transglutaminase enzyme known as factor XIIa is activated.If an injury occurs, the fibrinolytic system will activate to limit the size of the clot. This system begins with the release of the plasminogen activator from the vascular endothelial cells to allow this molecule to bind to the fibrin surface of plasmin. Fibrin-bound plasmin will then degrade the fibrin network into several soluble fragments, of which will include the D-dimer of the (DD)E complex.