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Anti-BCMA bispecific antibody (DM4)
Anti-BCMA bispecific antibody (DM4)
- 中文名称:
- Anti-BCMA bispecific antibody (DM4)
- 英文名称:
- Anti-BCMA bispecific antibody (DM4)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47173
- 规格:
- 0.01 mg|0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议:
- Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- FCM/FACS (Flow Cytometry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:Rabbit scfv
克隆号:[DM4]
特异性:N/A
纯度:Purified from cell culture supernatant by affinity chromatography
形式:Liquid; 0.1% Procline 300; 50% Glycerol; PBS, pH7.4; 0.1% BSA
浓度:N/A
- 说明书:
BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody, and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]