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Anti-SIRPalpha antibody (DM8), Rabbit mAb
Anti-SIRPalpha antibody (DM8), Rabbit mAb
- 中文名称:
- Anti-SIRPalpha antibody (DM8), Rabbit mAb
- 英文名称:
- Anti-SIRPalpha antibody (DM8), Rabbit mAb
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47174
- 规格:
- 0.01 mg|0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议:
- Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human
- 应用:
- IF (Immunofluorescence), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:Rabbit IgG
克隆号:[DM8]
特异性:N/A
纯度:Purified from cell culture supernatant by affinity chromatography
形式:Liquid; 50% Glycerol; PBS, pH7.4; 0.1% BSA
浓度:N/A
- 说明书:
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]