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Anti-Hsp90 Monoclonal Antibody
Anti-Hsp90 Monoclonal Antibody
- 中文名称：
- Anti-Hsp90 Monoclonal Antibody
- 英文名称：
- Anti-Hsp90 Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA47749
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, mouse, rat
- 应用：
- IB (Immunoblot), IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[4F3.E8]
特异性:Hsp90
This antibody recognizes human, mouse, and rat Hsp90alpha and beta. Other species have not been tested.
纯度:N/A
形式：100ug Protein G-purified antibody in PBS, pH 7.4.
浓度：N/A
- 说明书：
Hsp90 is an abundantly and ubiquitously expressed heat shock protein found in all eukaryotic cells. It exists in two principal forms, alpha and beta, which share 85% sequence homology. Both forms are expressed in the cytosol. Hsp90alpha exists primarily as a homodimer while Hsp90beta exists mainly as a monomer. Hsp90 plays a role in folding, assembly, maturation, and stabilization of specific proteins as a key component of a chaperone complex. Most of the Hsp90-regulated proteins that have been identified are involved in cell signaling; kinases, v-Src, Wee1, c-Raf, and p53 are some examples. When bound to ATP, Hsp90 interacts with cochaperones Cdc37, p23, and various immunophilin-like proteins to form complexes that stabilize and protect target proteins from proteasomal degradation.
