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Anti-Bim (IN) Antibody
Anti-Bim (IN) Antibody
- 中文名称:
- Anti-Bim (IN) Antibody
- 英文名称:
- Anti-Bim (IN) Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47903
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- N/A
- 应用:
- IB (Immunoblot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:N/A
同型:N/A
克隆号:N/A
特异性:Anti-Bim (IN) [Rabbit antibody to peptide corresponding to aa 22-40 of human Bim, a novel BH3 domain-containing protein. Recognizes human, mouse, and rat Bim.]
This antibody recognizes full-length Bim (23 kD) of human, mouse, and rat.
纯度:N/A
形式:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
浓度:N/A
- 说明书:
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain, and BH3 domain-containing pro-apoptotic proteins (such as Bad, Bax, Bid, Bik, and Hrk) form a growing subclass of the Bcl-2 family. A novel BH3 domain-containing protein was recently identified and designated Bim or BOD from human, mouse, and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 subfamily including Bcl-2, Bcl-xL, and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.