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TNFa (BSB-141)
TNFa (BSB-141)
- 中文名称：
- TNFa (BSB-141)
- 英文名称：
- TNFa (BSB-141)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59352
- 规格：
- 5 Slides|0.1 mL (Concentrate)|3 mL (RTU)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Mouse, Rat
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[BSB-141]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
TNFa-IP2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
Tumor Necrosis Factor alpha Induced-Protein 2 (also known as B94) is a 73?kDa polypeptide involved in pathways of inflammation, metastasis, tumor vasculature, and angiogenesis. The protein has an exocyst complex, Dsl1 complex, conserved oligomeric Golgi (COG) complex and the Golgi?associated retrograde protein (GARP) complex.
TNFa-IP2 antibody expression is found in epithelial cells, and immune cells exposed to Tumor Necrosis Factor alpha (TNFa), IL-1beta, LPS, interferon-y, Retinoic Acid, Latent Membrane Protein 1 (LMP1), and other pro-inflammatory cytokines. TNFa-IP can inhibit NFKB to further reduce inflammation in renal dysfunction and septic shock. and can interact with GTPases to regulate breast cancer and HeLa cell actin cytoskeleton and cell structure. TNFa-IP2 also participates in T-cell migration as an inflammatory regulator of chemokine secretion, and promotes metastasis and microvessel formation in nasopharyngeal carcinoma.
