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FGFR-3 (BSB-150)
FGFR-3 (BSB-150)
- 中文名称：
- FGFR-3 (BSB-150)
- 英文名称：
- FGFR-3 (BSB-150)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59368
- 规格：
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[BSB-150]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
FGFR-3 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
The FGFR3 gene encodes the protein Fibroblast Growth Factor Receptor 3 (FGFR3), part of a family of four fibroblast growth factor receptors that share similar structures and functions. These proteins play a role in several important cellular processes, including regulation of cell growth and proliferation, determination of cell type, angiogenesis, wound healing, and embryo development.
Approximately 80% of Non-Muscle Invasive Bladder Cancer (NMIBC) tumors have FGFR3 gene mutations. In addition to high prevalence in Bladder Cancer, somatic mutations in the FGFR3 gene have been associated with Multiple Myeloma and Cervical Cancer. FGFR3 gene aberrations have also been reported in Urothelial, Breast, Head/Neck, Lung, Brain, Gastric, Pancreatic, Colorectal, Kidney, Endometrial, Ovarian, and Cervical Cancers. FGFR-3 antibody, which is highly expressed in Cutaneous Malignant Melanoma (CMM) tissues, is correlated with increased Breslow thickness and lymph node metastasis.
