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IFN-Gamma (BSB-161)
IFN-Gamma (BSB-161)
- 中文名称：
- IFN-Gamma (BSB-161)
- 英文名称：
- IFN-Gamma (BSB-161)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59378
- 规格：
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[BSB-161]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
Anti-IFN-y is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
IFN-gamma is a dimerized soluble cytokine and the only member of the type II interferon. In humans, IFN-gamma is encoded by the IFNG gene and is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocytes effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-gamma is also produced by non-cytotoxic innate lymphoid cells.
IFN-gamma interacts with its receptors interferon gamma receptor 1 and interferon gamma receptor 2 and activates them. IFN-gamma binding to the receptors activates the JAK-STAT pathway. IFN-gamma also binds to the glycosaminoglycan heparan sulfate and inhibits its biological activity. IFN-gamma is used to treat Chronic Granulomatous Disease and Osteopetrosis, also has potential as cancer immunotherapy to improve survival in Bladder Carcinoma, Melanoma, and Ovarian Carcinoma.
