-
Somatostatin Receptor 2/SSTR2 (EP149)
Somatostatin Receptor 2/SSTR2 (EP149)
- 中文名称：
- Somatostatin Receptor 2/SSTR2 (EP149)
- 英文名称：
- Somatostatin Receptor 2/SSTR2 (EP149)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59391
- 规格：
- 3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)|15 mL (RTU)
- 保存建议：
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Mouse, Rat
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG
克隆号:[EP149]
特异性:N/A
纯度:N/A
形式：Paraffin, Frozen
Somatostatin Receptor 2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
Somatostatin Receptor 2 (SSTR2) is one of five subtypes of the somatostatin receptors, which belong to the superfamily of G protein-coupled receptors (GPCRs). Somatostatin receptor 2 is encoded by the SSTR2 gene, located on chromosome 17q25.1. SSTR2. SSTR2 becomes activated by the hormone somatostatin (SST), which is an inhibitor of hormone secretion and gastrointestinal function. SST and its receptor subtypes also prevent angiogenesis and have anti-proliferative effects on healthy and cancerous cells.
Somatostatin Receptors have been reported to be highly expressed in a wide variety of human tumors. High somatostatin receptor 2 antibody expression was found via IHC in neuroblastomas, medulloblastomas, paragangliomas, small cell lung cancers, meningiomas, and breast cancers. One study reported a highly specific and increased expression of somatostatin receptor 2 antibody in a large series of neural and neuroendocrine tumors. Another study investigating patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) demonstrated the correlation between decreased immunohistochemical staining and advanced stage of tumors. Additionally, an improved survival of patients with high SSTR2 expression was found, indicating the usefulness of SSTR2 as a potential prognostic marker for GEP-NEN.
