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SOX-2 (RM427)
SOX-2 (RM427)
- 中文名称:
- SOX-2 (RM427)
- 英文名称:
- SOX-2 (RM427)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59412
- 规格:
- 0.1 mL (Concentrate)|3 mL (RTU)|0.5 mL (Concentrate)|7 mL (RTU)|15 mL (RTU)
- 保存建议:
- Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Predicted: Mouse
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG
克隆号:[RM427]
特异性:N/A
纯度:N/A
形式:Paraffin, Frozen
Anti-SOX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
浓度:N/A
- 说明书:
SRY (sex determining region Y)-box 2, also known as SOX-2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. It is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach.
SOX-2 antibody is expressed in fetal brain and is used as a marker for multipotential neural stem cells. In tumors, SOX-2 expression is observed in teratoma of the central nervous system, melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and squamous cell carcinoma of the gastrointestinal tract. SOX-2 may be useful in the identification of embryonal carcinoma. In stage I lung adenocarcinomas, SOX2 seems to be an independent predictor of poor outcome and may help stratify patients at increased risk for recurrence.