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PiT1 (BSB-182), MMab
PiT1 (BSB-182), MMab
- 中文名称：
- PiT1 (BSB-182), MMab
- 英文名称：
- PiT1 (BSB-182), MMab
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59489
- 规格：
- 5 Slides|3 mL (RTU)|0.1 mL (Concentrate)|7 mL (RTU)|0.5 mL (Concentrate)
- 保存建议：
- 请按照说明书指示
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b
克隆号:[BSB-182]
特异性:N/A
纯度:N/A
形式：TFF3 is a mouse monoclonal antibody for immunohistochemistry derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized, and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
浓度：N/A
- 说明书：
POU1F1 is a tissue specific transcription factor that regulates gene expression, particularly in somatotrophs, lactotrophs, and thyrotrophs, found in the developing anterior pituitary. The POU class 1 homeobox 1 transcription factor (POU1F1, also known as Pit-1) was originally detected in the pituitary gland and is expressed in the mammary gland; it can regulate cell differentiation and is an activator for pituitary gene transcription during organogenesis.
Pit-1 deregulation induces a malignant phenotype in breast cancer cells associated with tumor growth and metastasis. One study determined that Pit-1 was detected in human placenta, human breast adenocarcinoma cell line, and hematopoietic and lymphoid tissues. Moreover, abnormal expression of Pit-1 in these tissues was reported to be associated with tumor progression. In another study, an increased expression level of Pit-1 was found in exponentially growing human myeloid leukemic cells, and the level was specifically associated with cell proliferation.
